Publications

 

Chronocort® Publications

Mallappa et al (2015). A Phase 2 study of Chronocort®, a modified-release formulation of hydrocortisone, in the treatment of adults with classic congenital adrenal hyperplasia. The Journal of Clinical Endocrinology & Metabolism. Doi 10.1210/jc.2014-3809.

Whitaker et al (2014). An oral multiparticulate, modified-release, hydrocortisone replacement therapy that provides physiological cortisol exposure. Clinical Endocrinology. 80, 554-561.

Debono and Ross (2013). What is the best approach to tailoring hydrocortisone dose to meet patient needs in 2012? Clinical Endocrinology. 78, 659-664. Doi: 10.1111/cen.12117.

Debono et al (May 2009). Modified release hydrocortisone to provide circadian cortisol profiles. The Journal of Clinical Endocrinology & Metabolism. 94(5): 1548-1554.

Debono et al (2009). Novel strategies for hydrocortisone replacement. Best Practice & Research Clinical Endocrinology & Metabolism 23. 221-232.

Newell Price et al (2008). Modified-release hydrocortisone for circadian therapy: a proof-of-principle study in dexamethasone-suppressed normal volunteers. Clinical Endocrinology. 68, 130-135. Doi: 10.1111/j.1365-2265.2007.03011x

 

Infacort® Publications

Ruggieri et al. Successful private-public funding of paediatric medicines research: lessons from the EU programme to fund research into off-patent medicines. Eur J Pediatr; DOI 10.1007/s00431-014-2398-z.

Whitaker et al. Development and testing in healthy adults of oral hydrocortisone granules with taste masking for the treatment of neonates and infants with adrenal insufficiency.The Journal of Clinical Endocrinology & Metabolism, April 2015, 100(4):1681-1688; DOI 10.1210/jc.2014-4060.
 

Congenital Adrenal Hyperplasia Publications

Arlt et al (November 2010). Health status of adults with Congenital Adrenal Hyperplasia: A cohort study of 203 patients. The Journal of Clinical Endocrinology & Metabolism. 95(11): 5110-5121.

Merke and Bornstein (2005). Congenital Adrenal Hyperplasia. Lancet; 365: 2125-36.

 

Adrenal Insufficiency Publications

Arlt and Allolio (2003). Adrenal Insufficiency. Lancet; 361: 1881-93.